Research Achievements

2022.01.18

Oscillatory brain network changes after transcranial magnetic stimulation treatment in patients …

Drs. Ryo Mitoma and Yoji Hirano, in the Department of Neuropsychiatry, have published a novelpaper in the peer-reviewed journal, Journal of Affective Disorders Reports.
Oscillatory brain network changes after transcranial magnetic stimulation treatmentin patients with major depressive disorder
Ryo Mitoma, Shunsuke Tamura, Hiroshi Tateishi, Takako Mitsudo, Ichiro Tanabe, AkiraMonji,Yoji Hirano*
10.1111/bph.15920
Oscillatory Brain Network Changes after rTMS for Treatment-resistant Depression
- Possible Biomarker for rTMS Treatment -
PRESS RELEASE(Jan, 5, 2022)
Participating in a six-week repetitive transcranial magnetic stimulation (rTMS) treatment in patientswith treatment-resistant depression appears to make measurable oscillatory brain network changesassociated with improved cognitive function.

In a study that appeared in the Jan. 3 issue of Journal of Affective Disorders Reports , a teamled by Kyushu University Hospital (Yoji Hirano, Ryo Mitoma, and Shunsuke Tamura), withcollaboration with Saga University Hospital (Hiroshi Tateishi and Akira Monji), reported the resultsof their study, the first to document oscillatory brain network changes in theta-band (left figure)and increased resting-state gamma power (right figure) after rTMS for treatmentresistantdepression using clinical EEG settings. The results suggest that the connectivity indices of neuraloscillations that are detectable using clinical EEG can be used as neurophysiological markers of theeffects of rTMS on cognitive function in patients with treatment-resistant depression.
Title: Oscillatory brain network changes after transcranial magnetic stimulation treatment inpatients with major depressive disorder
Authors: Ryo Mitoma, Shunsuke Tamura, Hiroshi Tateishi, Takako Mitsudo, Ichiro Tanabe, AkiraMonji, Yoji Hirano* Journal : Journal of Affective Disorders Reports
DOI: https://doi.org/10.1016/j.jadr.2021.100277
Corresponding Author: Yoji Hirano M.D., Ph.D
Affiliation : Department of Neuropsychiatry, Kyushu University, Fukuoka, Japan
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